• 1622 Citations
  • 20 h-Index
1988 …2019

Research output per year

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Research Output

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Article
2019
Open Access
2018
2 Scopus citations

Mice lacking L-12/15-lipoxygenase show increased mortality during kindling despite demonstrating resistance to epileptogenesis

Kanzler, M. A., Van Dyke, A. M., He, Y., Hewett, J. & Hewett, S., Jan 1 2018, In : Epilepsia Open. 3, 2, p. 255-263 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2016
6 Scopus citations
7 Scopus citations
2015

A cytotoxic, co-operative interaction between energy deprivation and glutamate release from system xc-mediates aglycemic neuronal cell death

Thorn, T. L., He, Y., Jackman, N. A., Lobner, D., Hewett, J. A. & Hewett, S. J., Nov 9 2015, In : ASN Neuro. 7, 6

Research output: Contribution to journalArticle

4 Scopus citations
2012

Neuromodulatory role of endogenous interleukin-1β in acute seizures: Possible contribution of cyclooxygenase-2

Claycomb, R. J., Hewett, S. J. & Hewett, J. A., Jan 1 2012, In : Neurobiology of Disease. 45, 1, p. 234-242 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Non-cell autonomous influence of the astrocyte system X-c on hypoglycaemic neuronal cell death

Jackman, N. A., Melchior, S. E., Hewett, J. A. & Hewett, S. J., Jan 1 2012, In : ASN Neuro. 4, 1, p. 23-32 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
2011

Prophylactic, prandial rofecoxib treatment lacks efficacy against acute PTZ-induced seizure generation and kindling acquisition

Claycomb, R. J., Hewett, S. J. & Hewett, J. A., Feb 1 2011, In : Epilepsia. 52, 2, p. 273-283 11 p.

Research output: Contribution to journalArticle

24 Scopus citations
2010

Regulation of system xc-activity and expression in astrocytes by interleukin-1β: Implications for hypoxic neuronal injury

Jackman, N. A., Uliasz, T. F., Hewett, J. A. & Hewett, S. J., Nov 15 2010, In : GLIA. 58, 15, p. 1806-1815 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Smad3-dependent signaling underlies the TGF-β1-mediated enhancement in astrocytic iNOS expression

Hamby, M. E., Hewett, J. A. & Hewett, S. J., Aug 15 2010, In : GLIA. 58, 11, p. 1282-1291 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2008

Cytosolic phospholipase A2α inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death

Taylor, A. L., Bonventre, J. V., Uliasz, T. F., Hewett, J. A. & Hewett, S. J., Aug 1 2008, In : Journal of Neurochemistry. 106, 4, p. 1828-1840 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

TGFβ1 and TNFα potentiate nitric oxide production in astrocyte cultures by recruiting distinct subpopulations of cells to express NOS-2

Hamby, M. E., Gragnolati, A. R., Hewett, S. J. & Hewett, J. A., May 1 2008, In : Neurochemistry International. 52, 6, p. 962-971 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
10 Scopus citations
2006

Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes

Hamby, M. E., Uliasz, T. F., Hewett, S. J. & Hewett, J. A., Jan 15 2006, In : Journal of Neuroscience Methods. 150, 1, p. 128-137 10 p.

Research output: Contribution to journalArticle

86 Scopus citations

Oral treatment with rofecoxib reduces hippocampal excitotoxic neurodegeneration

Hewett, S. J., Silakova, J. M. & Hewett, J. A., Nov 24 2006, In : Journal of Pharmacology and Experimental Therapeutics. 319, 3, p. 1219-1224 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

TGF-β1 potentiates astrocytic nitric oxide production by expanding the population of astrocytes that express NOS-2

Hamby, M. E., Hewett, J. A. & Hewett, S. J., Nov 1 2006, In : GLIA. 54, 6, p. 566-577 12 p.

Research output: Contribution to journalArticle

51 Scopus citations
2005

Cloning and characterization of cyclooxygenase-1b (putative cyclooxygenase-3) in rat

Snipes, J. A., Kis, B., Shelness, G. S., Hewett, J. A. & Busija, D. W., May 1 2005, In : Journal of Pharmacology and Experimental Therapeutics. 313, 2, p. 668-676 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Interleukin-1β potentiates neuronal injury in a variety of injury models involving energy deprivation

Fogal, B., Hewett, J. A. & Hewett, S. J., Apr 2005, In : Journal of Neuroimmunology. 161, 1-2, p. 93-100 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2004

Naproxen reduces excitotoxic neurodegeneration in vivo with an extended therapeutic window

Silakova, J. M., Hewett, J. A. & Hewett, S. J., Jun 1 2004, In : Journal of Pharmacology and Experimental Therapeutics. 309, 3, p. 1060-1066 7 p.

Research output: Contribution to journalArticle

26 Scopus citations
2001

Differential modulation of prostaglandin H synthase-2 by nitric oxide-related species in intact cells

Vidwans, A. S., Uliasz, T. F., Hewett, J. A. & Hewett, S. J., Sep 25 2001, In : Biochemistry. 40, 38, p. 11533-11542 10 p.

Research output: Contribution to journalArticle

22 Scopus citations
2000
220 Scopus citations
1999

Inducible nitric oxide synthase expression in cultures enriched for mature oligodendrocytes is due to microglia

Hewett, J. A., Hewett, S. J., Winkler, S. & Pfeiffer, S. E., May 1 1999, In : Journal of Neuroscience Research. 56, 2, p. 189-198 10 p.

Research output: Contribution to journalArticle

48 Scopus citations
1995
48 Scopus citations
1994

Methylene dianiline hepatotoxicity is not leukocyte-dependent

Bailie, M. B., Hewett, J. A., Schultze, A. E. & Roth, R. A., Jan 1994, In : Toxicology and Applied Pharmacology. 124, 1, p. 25-30 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
1993

Relationship between tumor necrosis factor-α and neutrophils in endotoxin-induced liver injury

Hewett, J. A., Jean, P. A., Kunkel, S. L. & Roth, R. A., Dec 1 1993, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 265, 6 28-6, p. G1011-G1015

Research output: Contribution to journalArticle

142 Scopus citations
1992

Neutrophil depletion protects against liver injury from bacterial endotoxin

Hewett, J. A., Schultze, A. E., VanCise, S. & Roth, R. A., Jan 1 1992, In : Laboratory Investigation. 66, 3, p. 347-361 15 p.

Research output: Contribution to journalArticle

165 Scopus citations
1990

The cholestatic agent, α-naphthylisothiocyanate, stimulates superoxide release by rat neutrophils in vitro

Roth, R. A. & Hewett, J. A., Jan 1 1990, In : Laboratory Investigation. 62, 6, p. 736-741 6 p.

Research output: Contribution to journalArticle

19 Scopus citations
1988

Bile and bile salts potentiate superoxide anion release from activated, rat peritoneal neutrophils

Dahm, L. J., Hewett, J. A. & Roth, R. A., Aug 1988, In : Toxicology and Applied Pharmacology. 95, 1, p. 82-92 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Dieldrin activates rat neutrophils in vitro

Hewett, J. A. & Roth, R. A., Nov 1988, In : Toxicology and Applied Pharmacology. 96, 2, p. 269-278 10 p.

Research output: Contribution to journalArticle

24 Scopus citations