Projects per year
Fingerprint Dive into the research topics where James Hewett is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Astrocytes
Medicine & Life Sciences
Cyclooxygenase 2
Medicine & Life Sciences
Lipopolysaccharides
Medicine & Life Sciences
Wounds and Injuries
Medicine & Life Sciences
Neutrophils
Medicine & Life Sciences
Microglia
Medicine & Life Sciences
Nitric Oxide
Medicine & Life Sciences
Transforming Growth Factors
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2011 2018
- 6 Finished
Cyclooxygenase-2: An Endogenous Neuromodulator in Seizures and Epileptogenesis
National Institute of Neurological Disorders and Stroke/NIH/DHHS
9/1/14 → 8/31/17
Project: Research project
IL-1 in Protection and Injury
National Institute of Neurological Disorders and Stroke/NIH/DHHS
9/15/13 → 6/30/18
Project: Research project
IL-1 in Protection and Injury-Diversity Supplement
National Institute of Neurological Disorders and Stroke/NIH/DHHS
9/15/13 → 8/31/15
Project: Research project
Constructing an Conditional Slc7a11 (xCT) Null Mouse
National Institute of Neurological Disorders and Stroke/NIH/DHHS
7/15/11 → 6/30/15
Project: Research project
Research Output 1988 2019
Decreased epileptogenesis in mice lacking the System x c − transporter occurs in association with a reduction in AMPA receptor subunit GluA1
Sears, S. M. S., Hewett, J. & Hewett, S., Mar 1 2019, In : Epilepsia Open. 4, 1, p. 133-143 11 p.Research output: Contribution to journal › Article
Open Access
AMPA Receptors
Pentylenetetrazole
Cysteine
Glutamic Acid
Epilepsy
1
Citation
(Scopus)
Maintenance of the Innate Seizure Threshold by Cyclooxygenase-2 is Not Influenced by the Translational Silencer, T-cell Intracellular Antigen-1
Gong, Y. & Hewett, J., Mar 1 2018, In : Neuroscience. 373, p. 37-51 15 p.Research output: Contribution to journal › Article
Cyclooxygenase 2
Seizures
Maintenance
T-Lymphocytes
Antigens
1
Citation
(Scopus)
Mice lacking L-12/15-lipoxygenase show increased mortality during kindling despite demonstrating resistance to epileptogenesis
Kanzler, M. A., Van Dyke, A. M., He, Y., Hewett, J. & Hewett, S., Jan 1 2018, In : Epilepsia Open. 3, 2, p. 255-263 9 p.Research output: Contribution to journal › Article
Open Access
Mortality
Seizures
12-15-lipoxygenase
Messenger RNA
Pentylenetetrazole
5
Citations
(Scopus)
Interleukin 1β regulation of the system xc - substrate-specific subunit, xCT, in primary mouse astrocytes involves the RNA-binding protein HuR
Shi, J., He, Y., Hewett, S. & Hewett, J., Jan 22 2016, In : Journal of Biological Chemistry. 291, 4, p. 1643-1651 9 p.Research output: Contribution to journal › Article
RNA-Binding Proteins
Interleukin-1
Astrocytes
Substrates
Messenger RNA
7
Citations
(Scopus)
Spontaneous glutamatergic synaptic activity regulates constitutive COX-2 expression in neurons: Opposing roles for the transcription factors CREB (cAMP response element binding) protein and Sp1 (stimulatory protein-1)
Hewett, S., Shi, J., Gong, Y., Dhandapani, K., Pilbeam, C. & Hewett, J., Dec 30 2016, In : Journal of Biological Chemistry. 291, 53, p. 27279-27288 10 p.Research output: Contribution to journal › Article
Cyclic AMP Response Element-Binding Protein
Neurons
Transcription Factors
Luciferases
Prostaglandin-Endoperoxide Synthases
Press and Media
BIOLOGISTS AWARDED NIH GRANT TO STUDY ORIGINS OF BRAIN DISORDERS
6/13/18
1 item of Media coverage
Press/Media: Expert Comment
Epilepsy: Biologists link protein, seizure suppression
3/8/18
1 item of Media coverage
Press/Media: Expert Comment
Scientists link protein to seizure suppression
3/8/18
1 item of Media coverage
Press/Media: Expert Comment
Severe Electrical Storms in the Brain - Biologists Link Protein, Seizure Suppression
3/8/18
1 item of Media coverage
Press/Media: Expert Comment
Severe Electrical Storms in the Brain -- Researchers Link Protein, Seizure Suppression
3/8/18
1 item of Media coverage
Press/Media: Expert Comment