• 547 Citations
  • 13 h-Index
20072023
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Research Output 2007 2019

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Article
2019
4 Citations (Scopus)

ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner

Dao, T. P., Martyniak, B., Canning, A. J., Lei, Y., Colicino, E. G., Cosgrove, M. S., Hehnly, H. & Castaneda, C., Jun 4 2019, In : Structure. 27, 6, p. 937-951.e5

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Amino Acids
Mutation
X-Linked Genes
Ultracentrifugation

Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes

Colicino, E. G., Stevens, K., Curtis, E., Rathbun, L., Bates, M., Manikas, J., Amack, J., Freshour, J. & Hehnly, H., Jun 15 2019, In : Molecular biology of the cell. 30, 13, p. 1598-1609 12 p.

Research output: Contribution to journalArticle

Open Access
Spindle Poles
Centrosome
Chromosomes
Centrioles
Spindle Apparatus
2018
3 Citations (Scopus)

Gravin regulates centrosome function through PLK1

Colicino, E. G., Garrastegui, A. M., Freshour, J., Santra, P., Post, D. E., Kotula, L. & Hehnly, H., Mar 1 2018, In : Molecular Biology of the Cell. 29, 5, p. 532-541 10 p.

Research output: Contribution to journalArticle

Centrosome
Chromosome Segregation
Chromosomes
Kinetochores
Biosensing Techniques
2 Citations (Scopus)

Regulating a key mitotic regulator, polo-like kinase 1 (PLK1)

Colicino, E. G. & Hehnly, H., Jan 1 2018, (Accepted/In press) In : Cytoskeleton.

Research output: Contribution to journalArticle

Mitosis
Cell Division
Phosphotransferases
M Phase Cell Cycle Checkpoints
Kinetochores
2016
10 Citations (Scopus)

Focal adhesions control cleavage furrow shape and spindle tilt during mitosis

Taneja, N., Fenix, A. M., Rathbun, L., Millis, B. A., Tyska, M. J., Hehnly, H. & Burnette, D. T., Jul 19 2016, In : Scientific Reports. 6, 29846.

Research output: Contribution to journalArticle

Focal Adhesions
Mitosis
Stem Cells
Paxillin
Vinculin
27 Citations (Scopus)

The centrosome, a multitalented renaissance organelle

Vertii, A., Hehnly, H. & Doxsey, S., Jan 1 2016, In : Cold Spring Harbor perspectives in biology. 8, 12, a025049.

Research output: Contribution to journalArticle

Centrosome
Organelles
Recycling
Endosomes
Cells
7 Citations (Scopus)

The Centrosome Undergoes Plk1-Independent Interphase Maturation during Inflammation and Mediates Cytokine Release

Vertii, A., Ivshina, M., Zimmerman, W., Hehnly, H., Kant, S. & Doxsey, S., May 23 2016, In : Developmental Cell. 37, 4, p. 377-386 10 p.

Research output: Contribution to journalArticle

Centrosome
Interphase
Cytokines
Inflammation
Phosphotransferases
12 Citations (Scopus)

The mother centriole appendage protein cenexin modulates lumen formation through spindle orientation

Hung, H. F., Hehnly, H. & Doxsey, S., Mar 21 2016, In : Current Biology. 26, 6, p. 793-801 9 p.

Research output: Contribution to journalArticle

Centrioles
centrioles
appendages
Microtubules
microtubules
2015
21 Citations (Scopus)

A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells

Hehnly, H., Canton, D., Bucko, P., Langeberg, L. K., Ogier, L., Gelman, I., Fernando Santana, L., Wordeman, L. & Scott, J. D., Sep 25 2015, In : eLife. 4, September, e09384.

Research output: Contribution to journalArticle

Spindle Poles
Seminoma
Spindle Apparatus
Seminiferous Tubules
Stem cells
3 Citations (Scopus)

Human Nek7-interactor RGS2 is required for mitotic spindle organization

De Souza, E. E., Hehnly, H., Perez, A. M., Meirelles, G. V., Smetana, J. H. C., Doxsey, S. & Kobarg, J., Feb 15 2015, In : Cell Cycle. 14, 4, p. 656-667 12 p.

Research output: Contribution to journalArticle

Spindle Apparatus
Spindle Poles
Microtubules
Phosphotransferases
Kinetochores
21 Citations (Scopus)

PKA-Type i Selective Constrained Peptide Disruptors of AKAP Complexes

Wang, Y., Ho, T. G., Franz, E., Hermann, J. S., Smith, F. D., Hehnly, H., Esseltine, J. L., Hanold, L. E., Murph, M. M., Bertinetti, D., Scott, J. D., Herberg, F. W. & Kennedy, E. J., Jun 19 2015, In : ACS Chemical Biology. 10, 6, p. 1502-1510 9 p.

Research output: Contribution to journalArticle

Protein Kinases
Phosphotransferases
Peptides
Protein Isoforms
Proteins
2014
6 Citations (Scopus)

A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection

Gammon, D. B., Duraffour, S., Rozelle, D. K., Hehnly, H., Sharma, R., Sparks, M. E., West, C. C., Chen, Y., Moresco, J. J., Andrei, G., Connor, J. H., Conte, D., Gundersen-Rindal, D. E., Marshall, W. L., Yates, J. R., Silverman, N. & Mello, C. C., Jun 25 2014, In : eLife. 2014, 3, 02190.

Research output: Contribution to journalArticle

RNA Virus Infections
DNA Viruses
Invertebrates
Viruses
Vertebrates
40 Citations (Scopus)

A Unique Set of Centrosome Proteins Requires Pericentrin for Spindle-Pole Localization and Spindle Orientation

Chen, C. T., Hehnly, H., Yu, Q., Farkas, D., Zheng, G., Redick, S. D., Hung, H. F., Samtani, R., Jurczyk, A., Akbarian, S., Wise, C., Jackson, A., Bober, M., Guo, Y., Lo, C. & Doxsey, S., Jan 1 2014, In : Current Biology. 24, 19, p. 2327-2334 8 p.

Research output: Contribution to journalArticle

Spindle Poles
centrosomes
Centrosome
dwarfing
Poles
2012
67 Citations (Scopus)

The centrosome regulates the Rab11- dependent recycling endosome pathway at appendages of the mother centriole

Hehnly, H., Chen, C. T., Powers, C. M., Liu, H. L. & Doxsey, S., Oct 23 2012, In : Current Biology. 22, 20, p. 1944-1950 7 p.

Research output: Contribution to journalArticle

Centrioles
centrosomes
Centrosome
centrioles
endosomes
2010
24 Citations (Scopus)

Cdc42 regulates microtubule-dependent golgi positioning

Hehnly, H., Xu, W., Chen, J. L. & Stamnes, M., Aug 1 2010, In : Traffic. 11, 8, p. 1067-1078 12 p.

Research output: Contribution to journalArticle

Dyneins
Microtubules
Centrosome
Nocodazole
Capsid Proteins
2009
30 Citations (Scopus)

Retrograde Shiga toxin trafficking is regulated by ARHGAP21 and Cdc42

Hehnly, H., Longhini, K. M., Chen, J. L. & Stamnes, M., Oct 15 2009, In : Molecular Biology of the Cell. 20, 20, p. 4303-4312 10 p.

Research output: Contribution to journalArticle

Shiga Toxin
Secretory Pathway
Endocytosis
Dyneins
Golgi Apparatus