Projects per year
Personal profile
Research Interests
- liquid-liquid phase separation
- protein quality control
- ubiquitin shuttle proteins
- protein structure and dynamics
- NMR spectroscopy
- microscopy
- cell stress
- biomolecular condensates
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Dive into the research topics where Carlos Castaneda is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Deciphering Molecular Mechanisms Underlying Liquid-liquid Phase Separation of Ubiquilin Proteins: CAREER
5/1/18 → 4/30/23
Project: Research project
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Molecular Basis and Effects of Ubiquilin-2 Phase Separation on Association with ALS-linked Proteins
10/1/17 → 9/30/20
Project: Research project
Research output
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Effects of Modulating Multivalent Ligand Binding Accessibility & Affinity on Liquid-Liquid Phase Separation
Galagedera, S. K., Dao, T. P. & Castaneda, C. A., May 1 2022, In: FASEB Journal. 36Research output: Contribution to journal › Article › peer-review
Open Access -
Polyubiquitin effects on phase transitions of shuttle protein UBQLN2
Castaneda, C. A., Dao, T. P. & Yang, Y., May 1 2022, In: FASEB Journal. 36Research output: Contribution to journal › Article › peer-review
Open Access -
ALS-linked mutations impair UBQLN2 stress-induced biomolecular condensate assembly in cells
Riley, J. F., Fioramonti, P. J., Rusnock, A. K., Hehnly, H. & Castañeda, C. A., Oct 2021, In: Journal of Neurochemistry. 159, 1, p. 145-155 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Mechanistic insights into the enhancement or inhibition of phase separation by polyubiquitin chains of different lengths or linkages
Dao, T. P., Yang, Y., Presti, M. F., Cosgrove, M. S., Hopkins, J. B., Ma, W., Loh, S. N. & Castañeda, C. A., Nov 13 2021Research output: Other contribution
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Previously uncharacterized interactions between the folded and intrinsically disordered domains impart asymmetric effects on UBQLN2 phase separation
Zheng, T., Galagedera, S. K. K. & Castañeda, C. A., Jul 2021, In: Protein Science. 30, 7, p. 1467-1481 15 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Press and Media
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Tension between structured complexes and disordered assemblies
9/24/21
1 item of Media coverage
Press/Media: Expert Comment
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Finding Beauty in Cell Stress
Carlos Castaneda & Heidi Hehnly
3/12/20
1 item of Media coverage
Press/Media: Expert Comment
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Understanding 'Disease Mechanisms' of ALS
Carlos Castaneda & Heidi Hehnly
3/12/18
1 item of Media coverage
Press/Media: Expert Comment
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Jordan Barrett, Maizy Ludden Named Goldwater Scholars
Carlos Castaneda, Kari Segraves, Jay Hubisz, Stephan Martin Wehrli, Rick Welsh, Joseph Paulsen & James T Spencer
5/1/17
1 item of Media coverage
Press/Media: Expert Comment