Projects per year
Personal profile
Research Interests
- liquid-liquid phase separation
- protein quality control
- ubiquitin shuttle proteins
- protein structure and dynamics
- NMR spectroscopy
- microscopy
- cell stress
- biomolecular condensates
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Dive into the research topics where Carlos Castaneda is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
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Deciphering Molecular Mechanisms Underlying Liquid-liquid Phase Separation of Ubiquilin Proteins: CAREER
5/1/18 → 4/30/23
Project: Research project
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Molecular Basis and Effects of Ubiquilin-2 Phase Separation on Association with ALS-linked Proteins
10/1/17 → 9/30/20
Project: Research project
Research Output
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Structure, dynamics and functions of UBQLNs: At the crossroads of protein quality control machinery
Zheng, T., Yang, Y. & Castañeda, C. A., 2020, In: Biochemical Journal. 477, 18, p. 3471-3497 27 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Ubiquitin-Modulated Phase Separation of Shuttle Proteins: Does Condensate Formation Promote Protein Degradation?
Dao, T. P. & Castañeda, C. A., Nov 1 2020, In: BioEssays. 42, 11, 2000036.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner
Dao, T. P., Martyniak, B., Canning, A. J., Lei, Y., Colicino, E. G., Cosgrove, M. S., Hehnly, H. & Castañeda, C. A., Jun 4 2019, In: Structure. 27, 6, p. 937-951.e5Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Kemp Eliminases of the AlleyCat Family Possess High Substrate Promiscuity
Caselle, E. A., Yoon, J. H., Bhattacharya, S., Rempillo, J. J. L., Lengyel, Z., D'Souza, A., Moroz, Y. S., Tolbert, P. L., Volkov, A. N., Forconi, M., Castañeda, C. A., Makhlynets, O. V. & Korendovych, I. V., Mar 6 2019, In: ChemCatChem. 11, 5, p. 1377 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Kemp Eliminases of the AlleyCat Family Possess High Substrate Promiscuity
Caselle, E. A., Yoon, J. H., Bhattacharya, S., Rempillo, J. J. L., Lengyel, Z., D'Souza, A., Moroz, Y. S., Tolbert, P. L., Volkov, A. N., Forconi, M., Castañeda, C. A., Makhlynets, O. V. & Korendovych, I. V., Mar 6 2019, In: ChemCatChem. 11, 5, p. 1425-1430 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Press and Media
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Finding Beauty in Cell Stress
Carlos Castaneda & Heidi Hehnly
3/12/20
1 item of Media coverage
Press/Media: Expert Comment
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Understanding 'Disease Mechanisms' of ALS
Carlos Castaneda & Heidi Hehnly
3/12/18
1 item of Media coverage
Press/Media: Expert Comment
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Jordan Barrett, Maizy Ludden Named Goldwater Scholars
Joseph Paulsen, James T Spencer, Carlos Castaneda, Kari Segraves, Joseph Richard Welsh, Jay Hubisz & Stephan Martin Wehrli
5/1/17
1 item of Media coverage
Press/Media: Expert Comment