Projects per year
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Ubiquitin
Medicine & Life Sciences
Polyubiquitin
Chemical Compounds
Proteins
Medicine & Life Sciences
Lysine
Chemical Compounds
leflunomide
Chemical Compounds
Micrococcal Nuclease
Medicine & Life Sciences
Proteasome Endopeptidase Complex
Medicine & Life Sciences
Water
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2014 2023
Deciphering Molecular Mechanisms Underlying Liquid-liquid Phase Separation of Ubiquilin Proteins: CAREER
5/1/18 → 4/30/23
Project: Research project
Molecular Basis and Effects of Ubiquilin-2 Phase Separation on Association with ALS-linked Proteins
10/1/17 → 9/30/20
Project: Research project
Research Output 2003 2019
4
Citations
(Scopus)
ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner
Dao, T. P., Martyniak, B., Canning, A. J., Lei, Y., Colicino, E. G., Cosgrove, M. S., Hehnly, H. & Castaneda, C., Jun 4 2019, In : Structure. 27, 6, p. 937-951.e5Research output: Contribution to journal › Article
Amyotrophic Lateral Sclerosis
Amino Acids
Mutation
X-Linked Genes
Ultracentrifugation
Kemp Eliminases of the AlleyCat Family Possess High Substrate Promiscuity
Caselle, E. A., Yoon, J. H., Bhattacharya, S., Rempillo, J. J. L., Lengyel, Z., D'Souza, A., Moroz, Y. S., Tolbert, P. L., Volkov, A. N., Forconi, M., Castaneda, C., Makhylnets, O. & Korendovych, I., Mar 6 2019, In : ChemCatChem. 11, 5, 1 p.Research output: Contribution to journal › Comment/debate
leflunomide
Catalysts
Communication
Substrates
Ukraine
Kemp Eliminases of the AlleyCat Family Possess High Substrate Promiscuity
Caselle, E. A., Yoon, J. H., Bhattacharya, S., Rempillo, J. J. L., Lengyel, Z., D'Souza, A., Moroz, Y. S., Tolbert, P. L., Volkov, A. N., Forconi, M., Castaneda, C., Makhylnets, O. & Korendovych, I., Jan 1 2019, In : ChemCatChem.Research output: Contribution to journal › Article
leflunomide
Prodrugs
Glutamic Acid
Enzymes
glutamates
Phase separation in biology and disease—a symposium report
Cable, J., Brangwynne, C., Seydoux, G., Cowburn, D., Pappu, R. V., Castaneda, C., Berchowitz, L. E., Chen, Z., Jonikas, M., Dernburg, A., Mittag, T. & Fawzi, N. L., Jan 1 2019, In : Annals of the New York Academy of Sciences.Research output: Contribution to journal › Comment/debate
Phase separation
RNA
Proteins
Huntington Disease
Amyotrophic Lateral Sclerosis
2
Citations
(Scopus)
Single Amino Acid Substitutions in Stickers, but Not Spacers, Substantially Alter UBQLN2 Phase Transitions and Dense Phase Material Properties
Yang, Y., Jones, H. B., Dao, T. P. & Castaneda, C., May 2 2019, In : Journal of Physical Chemistry B. 123, 17, p. 3618-3629 12 p.Research output: Contribution to journal › Article
Open Access
spacers
amino acids
Amino acids
Materials properties
Substitution reactions
Press and Media
Understanding 'Disease Mechanisms' of ALS
Carlos Castaneda & Heidi Hehnly
3/12/18
1 item of media coverage
Press/Media: Expert Comment
Jordan Barrett, Maizy Ludden Named Goldwater Scholars
Joseph Paulsen, James T Spencer, Carlos Castaneda, Kari Segraves, Joseph Richard Welsh, Jay Hubisz & Stephan Martin Wehrli
5/1/17
1 item of media coverage
Press/Media: Expert Comment