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Carlos Castaneda

 https://orcid.org/0000-0001-9634-0867

Accepting PhD Students

  • 1410 Citations
  • 20 h-Index
20032020

Research output per year

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Personal profile

Research Interests

  • liquid-liquid phase separation
  • protein quality control
  • ubiquitin shuttle proteins
  • protein structure and dynamics
  • NMR spectroscopy
  • microscopy
  • cell stress
  • biomolecular condensates

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Projects

Deciphering Molecular Mechanisms Underlying Liquid-liquid Phase Separation of Ubiquilin Proteins: CAREER

Castaneda, C.

National Science Foundation

5/1/18 → 4/30/23

Project: Research project

Molecular Basis and Effects of Ubiquilin-2 Phase Separation on Association with ALS-linked Proteins

Castaneda, C.

ALS Association

10/1/17 → 9/30/20

Project: Research project

Effects of Ubiquilin-2 ALS Mutations on Structure, Dynamics, and Interactions With Other ALS-Associated Proteins

Castaneda, C.

Amyotrophic Lateral Sclerosis Association (ALS)

8/1/16 → 7/31/17

Project: Research project

Utilization of a Shimadzu Triple-Quad to Address Critical Questions Pertaining to Peptide and Protein Post-Translational and Chemical Modifications

Castaneda, C. & Doyle, R. P.

Shimadzu Scientific Instruments

7/1/14 → 6/30/15

Project: Research project

Research Output

Ubiquitin-Modulated Phase Separation of Shuttle Proteins: Does Condensate Formation Promote Protein Degradation?

Dao, T. P. & Castañeda, C. A., 2020, (Accepted/In press) In : BioEssays.

Research output: Contribution to journal › Review article

    • ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner

    Dao, T. P., Martyniak, B., Canning, A. J., Lei, Y., Colicino, E. G., Cosgrove, M. S., Hehnly, H. & Castañeda, C. A., Jun 4 2019, In : Structure. 27, 6, p. 937-951.e5

    Research output: Contribution to journal › Article

    • 14 Scopus citations

    Kemp Eliminases of the AlleyCat Family Possess High Substrate Promiscuity

    Caselle, E. A., Yoon, J. H., Bhattacharya, S., Rempillo, J. J. L., Lengyel, Z., D'Souza, A., Moroz, Y. S., Tolbert, P. L., Volkov, A. N., Forconi, M., Castañeda, C. A., Makhlynets, O. V. & Korendovych, I. V., Mar 6 2019, In : ChemCatChem. 11, 5, p. 1377 1 p.

    Research output: Contribution to journal › Comment/debate

    • Kemp Eliminases of the AlleyCat Family Possess High Substrate Promiscuity

    Caselle, E. A., Yoon, J. H., Bhattacharya, S., Rempillo, J. J. L., Lengyel, Z., D'Souza, A., Moroz, Y. S., Tolbert, P. L., Volkov, A. N., Forconi, M., Castañeda, C. A., Makhlynets, O. V. & Korendovych, I. V., Mar 6 2019, In : ChemCatChem. 11, 5, p. 1425-1430 6 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Phase separation in biology and disease—a symposium report

    Cable, J., Brangwynne, C., Seydoux, G., Cowburn, D., Pappu, R. V., Castañeda, C. A., Berchowitz, L. E., Chen, Z., Jonikas, M., Dernburg, A., Mittag, T. & Fawzi, N. L., Sep 1 2019, In : Annals of the New York Academy of Sciences. 1452, 1, p. 3-11 9 p.

    Research output: Contribution to journal › Comment/debate

    • 3 Scopus citations

    Press and Media

    Finding Beauty in Cell Stress

    Carlos Castaneda & Heidi Hehnly

    3/12/20

    1 item of Media coverage

    Press/Media: Expert Comment

    ASBMB Today March 2019

    Carlos Castaneda

    3/12/19

    1 item of Media coverage

    Press/Media: Expert Comment

    Understanding 'Disease Mechanisms' of ALS

    Carlos Castaneda & Heidi Hehnly

    3/12/18

    1 item of Media coverage

    Press/Media: Expert Comment

    Jordan Barrett, Maizy Ludden Named Goldwater Scholars

    Joseph Paulsen, James T Spencer, Carlos Castaneda, Kari Segraves, Joseph Richard Welsh, Jay Hubisz & Stephan Martin Wehrli

    5/1/17

    1 item of Media coverage

    Press/Media: Expert Comment