Projects per year
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
Ubiquitin
Medicine & Life Sciences
Polyubiquitin
Chemical Compounds
Proteins
Medicine & Life Sciences
Lysine
Chemical Compounds
Micrococcal Nuclease
Medicine & Life Sciences
Proteasome Endopeptidase Complex
Medicine & Life Sciences
Water
Medicine & Life Sciences
Telomere
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2014 2023
Deciphering Molecular Mechanisms Underlying Liquid-liquid Phase Separation of Ubiquilin Proteins: CAREER
5/1/18 → 4/30/23
Project: Research project
Molecular Basis and Effects of Ubiquilin-2 Phase Separation on Association with ALS-linked Proteins
10/1/17 → 9/30/20
Project: Research project
Research Output 2003 2018
Cancer Mutations in SPOP Put a Stop to Its Inter-compartmental Hops
Riley, J. F., Dao, T. P. & Castaneda, C., Oct 4 2018, In : Molecular Cell. 72, 1, p. 1-3 3 p.Research output: Contribution to journal › Short survey
Humulus
Ubiquitination
Mutation
Neoplasms
8
Citations
Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions
Dao, T. P., Kolaitis, R-M., Kim, H. J., O'Donovan, K., Martyniak, B., Colicino, E., Hehnly, H., Taylor, J. P. & Castañeda, C. A., Mar 15 2018, In : Molecular Cell. 69, 6, p. 965-978.e6Research output: Contribution to journal › Article
RNA-Binding Proteins
Ubiquitin
Polyubiquitin
Organelles
Proteins
2
Citations
Functional tuning of the catalytic residue pKa in a de novo designed esterase
Hiebler, K., Lengyel, Z., Castaneda, C. & Makhylnets, O., 2017, (Accepted/In press) In : Proteins: Structure, Function and Bioinformatics.Research output: Contribution to journal › Article
Esterases
Histidine
Tuning
Static Electricity
Electrostatics
1
Citations
Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway
Nakasone, M. A., Lewis, T. A., Walker, O., Thakur, A., Mansour, W., Castaneda, C., Goeckeler-Fried, J. L., Parlati, F., Chou, T. F., Hayat, O., Zhang, D., Camara, C. M., Bonn, S. M., Nowicka, U. K., Krueger, S., Glickman, M. H., Brodsky, J. L., Deshaies, R. J. & Fushman, D., Dec 5 2017, In : Structure. 25, 12, p. 1839-1855.e11Research output: Contribution to journal › Article
Proteasome Endopeptidase Complex
Ubiquitin
Polyubiquitin
Ubiquitination
Protein Binding
16
Citations
Linkage-specific conformational ensembles of non-canonical polyubiquitin chains
Castaneda, C., Chaturvedi, A., Camara, C. M., Curtis, J. E., Krueger, S. & Fushman, D., 2016, In : Physical Chemistry Chemical Physics. 18, 8, p. 5771-5788 18 p.Research output: Contribution to journal › Article
Polyubiquitin
linkages
Lysine
Conformations
Crystal structure
Press and Media
Understanding 'Disease Mechanisms' of ALS
Carlos Castaneda & Heidi Hehnly
3/12/18
1 item of media coverage
Press/Media: Expert Comment
Jordan Barrett, Maizy Ludden Named Goldwater Scholars
Joseph Paulsen, James T Spencer, Carlos Castaneda, Kari Segraves, Joseph Richard Welsh, Jay Hubisz & Stephan Martin Wehrli
5/1/17
1 item of media coverage
Press/Media: Expert Comment